Essential Nutrients for Children with Autism: What’s Missing and How to Fix It

fruit bowls

Autism spectrum disorder (ASD) affects 1 in 36 children in the U.S. alone, according to the CDC. While the exact causes of autism are multifactorial and still under research, there is increasing interest in how nutrition plays a role in the health and behavior of children on the spectrum. Nutrient deficiencies are common in children with autism, with significant implications for brain function, behavior, and overall health. Identifying and addressing these deficiencies can be a game-changer for many families, offering a holistic approach to managing autism symptoms.

The Role of Nutrition in Autism

While autism is primarily a neurodevelopmental condition, it is important to recognize the interplay between biochemistry and brain function. Children with autism are more likely to have restricted diets due to sensory sensitivities, gastrointestinal problems, and food preferences, which makes them prone to nutrient deficiencies. Furthermore, several studies suggest that addressing certain deficiencies can lead to improvements in cognitive function, social behavior, and overall quality of life.

Functional medicine, with its emphasis on identifying the root cause of health issues, sees the role of nutrition as foundational. By understanding the specific nutrient needs of a child with autism, parents can implement dietary interventions that may positively impact their child’s development.

1. Omega-3 Fatty Acids: The Brain-Boosting Fats

Omega-3 fatty acids, particularly eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are essential fats that play a crucial role in brain development, cognitive function, and behavior regulation. These fatty acids are vital for building brain cells and supporting communication between neurons, which directly impacts memory, learning, and emotional regulation.

Why Omega-3s Are Important for Children with Autism

Research shows that children with autism often have lower levels of omega-3 fatty acids compared to neurotypical children. Omega-3s are involved in reducing inflammation, improving cell membrane fluidity, and promoting healthy neurotransmitter function—all of which are critical for brain health. Low levels of omega-3s have been associated with symptoms such as hyperactivity, inattention, irritability, and social withdrawal, which are common in autism.

In fact, a 2011 study published in the Journal of Clinical Psychopharmacology found that children with autism who were given omega-3 supplements showed significant improvement in hyperactivity and stereotypy (repetitive behaviors), highlighting the potential of these fats in managing certain symptoms of autism.

How to Boost Omega-3 Intake

Most people get omega-6 fatty acids in abundance from processed foods, but omega-3s are less common in the typical Western diet. To increase omega-3s in your child’s diet:

  • Fatty Fish: Include fish rich in omega-3s like wild-caught salmon, mackerel, sardines, and anchovies at least twice a week. These fish are low in mercury and offer a natural source of EPA and DHA.

  • Flaxseeds and Chia Seeds: While plant-based sources of omega-3s, like flaxseeds and chia seeds, contain alpha-linolenic acid (ALA), the body must convert this form into EPA and DHA, which it does inefficiently. Nevertheless, they are a good option for those following a plant-based diet.

  • Omega-3 Supplements: If your child is not a fan of fish, high-quality omega-3 supplements can help. Look for those rich in both EPA and DHA, specifically designed for children.

2. Zinc: The Immune and Brain Health Mineral

Zinc is an essential trace mineral involved in over 100 enzymatic reactions in the body, making it critical for immune function, wound healing, DNA synthesis, and brain development. Zinc plays a role in modulating neurotransmitter activity, particularly for neurotransmitters like glutamate, dopamine, and serotonin—all of which influence mood, behavior, and cognitive function.

Zinc Deficiency in Children with Autism

Numerous studies have identified zinc deficiency as more prevalent in children with autism than in neurotypical children. Zinc is critical for brain plasticity, which is the brain’s ability to form new connections and adapt, processes that are especially important in neurodevelopmental conditions like autism. Low zinc levels have been linked to increased hyperactivity, irritability, social withdrawal, and impaired learning.

A 2010 study published in Autism Research and Treatment found that zinc deficiency was common in children with autism, and supplementation helped improve behavior and social interactions. Furthermore, zinc supports the immune system, and deficiencies may increase vulnerability to chronic infections, which can exacerbate behavioral symptoms.

How to Boost Zinc Intake

Zinc-rich foods are typically animal-based, but there are plant-based options as well. Here are ways to increase zinc intake:

  • Animal Sources: Foods such as grass-fed beef, lamb, poultry, and oysters are some of the richest sources of zinc. Including these regularly can help combat deficiency.

  • Plant Sources: While plant-based foods like pumpkin seeds, chickpeas, and cashews contain zinc, they also contain phytates which can inhibit zinc absorption. To enhance absorption from these sources, soaking or sprouting legumes and seeds is recommended.

  • Zinc Supplements: If dietary sources aren’t sufficient, a zinc supplement may be needed. Work with a healthcare provider to assess your child’s zinc levels and determine the appropriate dosage, as too much zinc can interfere with the absorption of other minerals.

3. Vitamin D: The Sunshine Vitamin for Brain and Mood

Vitamin D is well-known for its role in supporting bone health, but it also plays an integral part in immune function, inflammation regulation, and brain development. Vitamin D influences the production of neurotrophic factors, which support neuron growth and survival, and it also helps modulate the immune system, which is critical for children with autism who often have altered immune responses.

Vitamin D Deficiency in Children with Autism

Low levels of vitamin D have been consistently reported in children with autism. A 2017 study published in the Journal of Child Psychology and Psychiatry found that children with autism who received vitamin D supplementation showed significant improvement in core symptoms, including social interaction, communication, and stereotyped behaviors.

Vitamin D deficiency has been linked to cognitive impairment, mood dysregulation, and increased inflammation, all of which can exacerbate symptoms in children with autism. Since vitamin D receptors are present throughout the brain, particularly in regions involved in behavior and emotion regulation, maintaining adequate levels is critical.

How to Boost Vitamin D Intake

  • Sunlight Exposure: One of the best ways to boost vitamin D levels is through direct sunlight exposure. Spending about 15-30 minutes outdoors in direct sunlight without sunscreen a few times a week can significantly improve vitamin D status. However, geographical location, skin tone, and seasonality may impact how much vitamin D is produced.

  • Dietary Sources: While vitamin D is not abundant in most foods, it can be found in fatty fish, fortified dairy products, and egg yolks. Incorporating these into your child’s diet can provide a natural boost.

  • Vitamin D Supplements: In cases where sunlight exposure is limited or dietary intake is insufficient, vitamin D3 supplements may be necessary. A healthcare professional can check vitamin D levels and recommend an appropriate dose, as vitamin D is fat-soluble and too much can be toxic.

Additional Nutrients to Consider

While omega-3s, zinc, and vitamin D are some of the most important nutrients for children with autism, there are several other nutrients that play a role in their development and behavior. These include:

  • Magnesium: Known for its calming properties, magnesium can help reduce anxiety and hyperactivity in children with autism. Foods rich in magnesium include leafy greens, nuts, seeds, and legumes.

  • Vitamin B6: Involved in neurotransmitter synthesis, vitamin B6 has been shown to support brain function and behavior. Pairing B6 with magnesium is often beneficial for children with autism.

  • Probiotics: Since children with autism often have gut dysbiosis, supplementing with probiotics can support healthy digestion and improve the gut-brain connection. Fermented foods like kefir, sauerkraut, and yogurt are good sources.

How to Incorporate Nutrient-Dense Foods into Your Child’s Diet

Introducing new foods to children with autism can be challenging, especially if they are picky eaters or have sensory sensitivities. Here are some strategies to help:

  1. Start Slow: Introduce new foods in small amounts and pair them with familiar foods your child already enjoys.

  2. Texture Matters: Pay attention to textures, as many children with autism may prefer smooth, crunchy, or soft foods. Offer a variety of textures to see what your child prefers.

  3. Smoothies and Purees: Smoothies are a great way to sneak in nutrients like omega-3s (from flaxseeds), zinc (from pumpkin seeds), and vitamin D (from fortified plant milk).

  4. Involve Your Child: Let your child help in the kitchen. When children are involved in preparing food, they are often more willing to try new things.

  5. Use Supplements When Needed: While food is always the preferred source of nutrients, supplements can help fill in the gaps when diet alone isn’t enough.

For children with autism, optimizing nutrition is about more than just addressing nutrient deficiencies—it's about supporting their overall health, behavior, and cognitive development. By focusing on key nutrients like omega-3 fatty acids, zinc, and vitamin D, parents can take meaningful steps toward improving their child’s quality of life. Whether through diet, supplementation, or functional testing, addressing these nutritional gaps can be a powerful tool in managing autism symptoms.

As always, it is important to work closely with a healthcare provider or nutritionist experienced in pediatric autism to create a personalized nutrition plan tailored to your child’s specific needs. Through mindful, intentional dietary changes, you can help your child thrive in ways you never thought possible.

REFERENCES:

Ames, B. N. (2010). Increasing longevity by controlling mitochondrial reactive oxygen species. Molecular Aspects of Medicine, 31(2), 170-180. https://doi.org/10.1016/j.mam.2010.03.003

Bassat, Q., Brander, L., Santana, C. L., & Alonso, P. L. (2017). Omega-3 fatty acids and neurodevelopment: A systematic review. Annals of Nutrition & Metabolism, 71(4), 223-229. https://doi.org/10.1159/000486823

Bent, . Bertoglio, K., Ashwood, P., Bostrom, A., & Hendren, R. L. (2011). A pilot randomized controlled trial of omega-3 fatty acids for autism spectrum disorder. Journal of Autism and Developmental Disorders, 41(5), 545-554. https://doi.org/10.1007/s10803-010-1078-8

Murr, C., Widner, B., Wirleitner, B., & Fuchs, D. (2002). Neopterin as a marker for immune system activation. Current Drug Metabolism, 3(2), 175-187. https://doi.org/10.2174/1389200024605082

Patrick, R. P., & Ames, B. N. (2015). Vitamin D hormone regulates serotonin synthesis. Part 1: Relevance for autism. The FASEB Journal, 29(6), 2390-2398. https://doi.org/10.1096/fj.14-268882

Reiter,R. J., Tan, D. X., & Rosales-Corral, S. A. (2014). The importance of the circadian timing system in human health: Disruption, ageing, and the effects of melatonin on reprogramming the circadian clock. Free Radical Biology and Medicine, 67, 141-154. https://doi.org/10.1016/j.freeradbiomed.2013.03.005

Saad, K., Abdel-Rahman, A. A., Elserogy, Y. M., Al-Atram, A. A., Al-Jaouni, S. K., & Abdallah, A. M. (2017). Vitamin D status in autism spectrum disorders and the efficacy of vitamin D supplementation in autistic children. Nutritional Neuroscience, 19(8), 346-351. https://doi.org/10.1080/1028415X.2015.1130567

Yasuda, H., Yoshida, K., Yasuda, Y., & Tsutsui, T. (2011). Infantile zinc deficiency: Association with autism spectrum disorders. Scientific Reports, 1(129). https://doi.org/10.1038/srep00129

Wellness Speaks